Biology MCQs for Class 12 with Answers Chapter 8 Human Health and Disease

Free PDF Download of CBSE Biology Multiple Choice Questions for Class 12 with Answers Chapter 8 Human Health and Disease. Biology MCQs for Class 12 Chapter Wise with Answers PDF Download was Prepared Based on Latest Exam Pattern. Students can solve NCERT Class 12 Biology Human Health and Disease MCQs Pdf with Answers to know their preparation level.

Human Health and Disease Class 12 Biology MCQs Pdf

1. In the immune system, interferons are a part of
(a) physiological barriers
(b) cellular barriers
(c) physical barriers
(d) cytokine barriers.

Answer

Answer: d


2. The letter T in T-lymphocytes refers to
(a) tonsil
(b) thalamus
(c) thymus
(d) thyroid

Answer

Answer: c


3. Use of anti-histamines and steroids gives a quick relief from
(a) allergy
(b) nausea
(c) cough
(d) fever

Answer

Answer: a


4. The immunoglobulin abundant in colostrum, is
(a) Ig D
(b) Ig A
(c) Ig G
(d) Ig M

Answer

Answer: b


5. Diacetyl morphine is commonly known as
(a) cocaine
(b) hashish
(c) ganja
(d) heroin

Answer

Answer: d


6. Opium is extracted from
(a) Atropa belladona
(b) Papaver somniferum
(c) Erythroxylum coca
(d) Cannabis sativa

Answer

Answer: b


7. The disease chikungunya is transmitted by
[NCERT Exemplar]
(a) houseflies
(b) Aedes mosquitoes
(c) cockroach
(d) female Anopheles

Answer

Answer: b


8. Anti venom against snake poison contains [NCERT Exemplar]
(a) antigens
(b) antigen-antibody complexes
(c) antibodies
(d) enzymes

Answer

Answer: c


9. Which of the following glands is large sized at birth but reducies in size with aging? [NCERT Exemplar]
(a) Pineal
(b) Pituitary
(c) Thymus
(d) Thyroid

Answer

Answer: c


10. The substance produced by a cell on viral infection that can protect other cells from further infection is [NCERT Exemplar]
(a) serotonin
(b) colostrum
(c) interferon
(d) histamine

Answer

Answer: c


11. Many diseases can be diagnosed by observing the symptoms in the patient. Which group of symptoms are indicative of pneumonia? [NCERT Exemplar]
(a) Difficulty in respiration, fever, chills, cough, headache
(b) Constipation, abdominal pain, cramps, blood clots
(c) Nasal congestion and discharge, cough, sorethroat, headache
(d) High fever, weakness, stomach pain, loss of appetite and constipation

Answer

Answer: a


12. Transplantation of tissues/organs to save certain patients often fails due to rejection of such tissues/organs by the patient. Which type of immune response is responsible for such rejections? [NCERT Exemplar]
(a) auto-immune response
(b) humoral immune response
(c) physiological immune response
(d) cell-mediated immune response

Answer

Answer: d


13. ______ mosquitoes are the vectors of dengue and chikungunya.

Answer/Explanation

Answer:
Explaination: Aedes.


14. ______ barriers protect the non-infected cells from further viral infections.

Answer/Explanation

Answer:
Explaination: Cytokine.


15. Cell-mediated immunity is provided by ______ .

Answer/Explanation

Answer:
Explaination: T-cells.


16. Among non-infectious diseases, ______ is the major cause of death.

Answer/Explanation

Answer:
Explaination: Cancer.


17. ______ test is performed to confirm typhoid.

Answer/Explanation

Answer:
Explaination: Widal.


18. Plasmodium enters the human body as ______ .

Answer/Explanation

Answer:
Explaination: Sporozoite.


19. ______ is the toxin released by the rupture of RBCs into the blood in a malaria- infected person.

Answer/Explanation

Answer:
Explaination: Hemocoin.


20. _____ is the filarial worm.

Answer/Explanation

Answer:
Explaination: Wuchereria.


21. ______ are the physical, chemical and biological agents that cause cancer.

Answer/Explanation

Answer:
Explaination: Carcinogens.


22. Heroin is obtained by _______ of morphine.

Answer/Explanation

Answer:
Explaination: Acetylation.


23. Match the organisms (Pathogens) in Column I with the diseases they cause in Column II.

Column I Column II
A. Rhino vims 1. Ringworm
B. Plasmodium 2. Filariasis
C. Salmonella 3. Common cold
D. Trichophyton 4. Typhoid
E. Wuchereria 5. Malaria
6. Amoebiasis
Answer/Explanation

Answer:
Explaination: A – 3, B – 5, C – 4, D-1, E – 2


24. Match the items in Column I with those in Column II.

Column I Column II
A. Physiological barrier 1. Interferons
B. Cytokine barrier 2. Skin of the body
C. Cellular barrier 3. Tear in the eyes
D. Physical barrier 4. Antibodies in colostrum
5. Polymorpho-nuclear leucocyte
Answer/Explanation

Answer:
Explaination: A – 3, B – 1, C – 5, D – 2


25. Humoral immunity is responsible for rejection of organ transplants. [True/False]

Answer/Explanation

Answer:
Explaination: False


26. a-interferon activates the immune system and help to destroy the tumour cells. [True/False]

Answer/Explanation

Answer:
Explaination: True


27. Cannabinoids affect the digestive system. [True/False]

Answer/Explanation

Answer:
Explaination: False


28. Nicotine, the alkaloid in tobacco causes the hallucinogenic effect. [True/False]

Answer/Explanation

Answer:
Explaination: False


29. Colostrum contains antibody IgA and provides passive immunity. [True/False]

Answer/Explanation

Answer:
Explaination: True


Directions (Q30 to Q33): Mark the odd one in each of the following groups.

30. Saliva in the mouth, Mucus coating in respiratory tract, Tear in the eyes, Acid in the stomach.

Answer/Explanation

Answer:
Explaination: Mucus coating in respiratory tract


31. Thymus, spleen, appendix, tonsil.

Answer/Explanation

Answer:
Explaination: Thymus


32. Charas, Heroin, Marijuana, Hashish.

Answer/Explanation

Answer:
Explaination: Heroin


33. Typhoid, Pneumonia, Diphtheria, Malaria.

Answer/Explanation

Answer:
Explaination: Malaria


34. Who discovered blood circulation in humans?

Answer/Explanation

Answer:
Explaination: William Harvey discovered blood circulation in humans.


35. Name one infectious and one non-infectious disease that is the major cause of mortality.

Answer/Explanation

Answer:
Explaination:
– Infectious disease – AIDS.
– Non-infectious disease – Cancer.


36. High fever, loss of appetite, stomach pain and constipation are some of the symptoms seen in a patient. How would the doctor confirm that the patient is suffering from typhoid and not amoebiasis?

Answer/Explanation

Answer:
Explaination: It would be confirmed by Widal test.


37. Name one respiratory disease that infects the lung alveoli and one that does not infect the lungs.

Answer/Explanation

Answer:
Explaination:
– Pneumonia infects lung alveoli.
– Common cold does not infect the lungs.


38. Name two diseases that spread by droplet infection.

Answer/Explanation

Answer:
Explaination: Common cold and pneumonia.


39. Name two diseases whose spread can be controlled by the eradication of Aedes mosquitoes. [CBSE 2918]
Or
Name two viral diseases transmitted by Aedes mosquito.

Answer/Explanation

Answer:
Explaination: Dengue and chikungunya.


40. Name the stage of Plasmodium that gains entry into the human, when bitten by an infected female Anopheles. [Delhi 2017C]

Answer/Explanation

Answer:
Explaination: Sporozoite is the stage.


41. Trace the route of Sporozoite at Plasmodium, when it enters the human body through the bite of female Anopheles, till its entry into RBCs. [Delhi 2017C]

Answer/Explanation

Answer:
Explaination: Into human blood → Liver cells → blood → RBCs.


42. Name the host where fertilisation occurs in the life cycle of Plasmodium [Delhi 2017C]

Answer/Explanation

Answer:
Explaination: Anopheles mosquito.


43. How does malaria differ from chikungunya with reference to their vectors? [All India 2010C]

Answer/Explanation

Answer:
Explaination:
– Anopheles mosquito is the vector of malaria.
– Aedes mosquito is the vector of chikungunya.


44. Malaria, typhoid, pneumonia and amoebiasis are some of the human infectious diseases. Which ones of these are transmitted through mechanical carriers? [Foreign 2011]

Answer/Explanation

Answer:
Explaination: Amoebiasis, typhoid.


45. How does haemozoin affect the human body, when released in blood during malarial infection? [Foreign 2014]

Answer/Explanation

Answer:
Explaination: Haemozoin causes the chill and high fever recurring at periodic intervals (of 3-4 days).


46. Why is Gamhusia introduced into drains and ponds? [AH India 2014]

Answer/Explanation

Answer:
Explaination: Gambusia feeds on the mosquito larvae and thereby helps in eliminating the mosquito vectors of the diseases like Malaria, Chikungunya, dengue, etc.


47. What causes swelling of the lower limbs in patients suffering from filariasis?

Answer/Explanation

Answer:
Explaination: The filarial worms live for many years in the lymphatic vessels of lower limbs and cause inflammation and swelling there.


48. What role do macrophages play in providing immunity to humans?

Answer/Explanation

Answer:
Explaination: Macrophages phagocytose and destroy the microbes (pathogens) and provide protection from diseases.


49. How do monocytes act as a cellular barrier in humans to provide innate immunity? [CBSE 2018 C]
Or
In what way is monocyte a cellular barrier w’ith reference to immunity? [Delhi 2015 C]

Answer/Explanation

Answer:
Explaination: Monocytes are phagocytic and destroy the pathogenic microbes.


50. How do neutrophils act as a cellular barrier to pathogens in humans?

Answer/Explanation

Answer:
Explaination: Neutrophils phagocytose and destroy the microbes (pathogens).


51. How do cytokine barriers provide innate immunity in humans? [CBSE 2018]
Or
How do cytokine barriers help in evading viral infections? [Delhi 2015 C]
Or
How do interferons protect us? [AH India 2012]

Answer/Explanation

Answer:
Explaination: Cytokine barriers, i.e. interferons are produced by the body cells in response to viral infection and protect the other non- infected cells from viral infection.


52. Name any two secretions in the body that act as ‘physiological barriers’ of innate immunity.

Answer/Explanation

Answer:
Explaination: Saliva in the mouth, acid in thestomach and tears from eyes. (any two)


53. Name the kind of barrier of innate immunity, where some cells secrete interferons when infected. [All India 2012]

Answer/Explanation

Answer:
Explaination: Cytokine barrier.


54. When does a human body elicit an anamnestic response? [AH India 2013]

Answer/Explanation

Answer:
Explaination: When a human body encounters a pathogen for the second time, it elicits an anamnestic response.


55. Why does a human being elicit an anamnestic response? [Delhi 2011C]

Answer/Explanation

Answer:
Explaination: Ahuman body elicits an anamnestic response Because our immune system appears to have memory of the first encounter with the same pathogen.


56. Suggest a method to ensure anamnestic response in humans. [Delhi 2017]

Answer/Explanation

Answer:
Explaination: Giving a booster dose of the vaccine can induce an anamnestic response.


57. Why is secondary immune response more intense than the primary immune response in humans? [All India 2014]

Answer/Explanation

Answer:
Explaination: Because body appears to have memory of the first encounter (in the form of memory B cells and memory T cells).


58. Why is the antibody-mediated immunity called humoral immunity? [HOTS]

Answer/Explanation

Answer:
Explaination: Antibodies are the glycoproteins that keep circulating in the body fluids (humors); hence, it is called humoral immunity.


59. Thymus of a new-born child was degenerating right from birth due to a genetic disorder. Predict its two impacts on the health of the child. [CBSE Sample Paper 2016]

Answer/Explanation

Answer:
Explaination:
– The number of T-lymphocytes will decrease and hence, the immune system will become weak.
– The child will become prone to any infection, which normally could be overcome.


60. Give two examples of passive immunity.

Answer/Explanation

Answer:
Explaination:
(i) The immunity provided by colostrum to the new-born.
(ii) The immunity provided to the foetus by the antibodies that pass through placenta from the mother.
(iii) Immunity provided against rabies and tetanus through inoculation.


61. Which category of adaptive immunity is provided by vaccination? Why? [HOTS]

Answer/Explanation

Answer:
Explaination: Active Immunity. It is called so because the antibodies are developed by the vaccinated person’s own cells in response to the antigens.


62. What is it that prevents a child to suffer from a disease he/she is vaccinated against? Give one reason. [Delhi 2010; HOTS]

Answer/Explanation

Answer:
Explaination:
– His body develops antibodies that circulate in the body fluids and neutralise the pathogenic agent during subsequent encounters.
– Memory B cells and memory T cells are retained in the system.


63. State the function of mast cells in allergy response. [Foreign 2013]

Answer/Explanation

Answer:
Explaination: Mast cells release chemicals like serotonin and hlitaminc, which cause allergy.


64. Why do pollen grains of some flowers trigger ‘sneezing’ in some people? [Foreign 2012]

Answer/Explanation

Answer:
Explaination: Pollen grains are allergens and cause allergic reactions in some people by causing release of histamine and serotonin from the mast cells.


65. Name the condition in vertebrates, where the body attacks self-cells. [All India 2017C]

Answer/Explanation

Answer:
Explaination: Autoimmunity.


66. Name the category of disease in which ’ ‘Rheumatoid arthritis’ in human, put under. [All India 2017 C]
Or
Name the category of the disease, rheumatoid arthritis. [Foreign 2012]

Answer/Explanation

Answer:
Explaination: Autoimmune disease.


67. What is an autoimmune disease? [All India 2017C]

Answer/Explanation

Answer:
Explaination: An autoimmune disease is the one caused when the immune system of the body goes off the track and attacks ‘self’ cells.


68. What would happen to the immune system, if thymus gland is removed from the body of a person?

Answer/Explanation

Answer:
Explaination:
– Thymus is a primary lymphoid organ.
– If that is removed, T-lymphocytes cannot differentiate and their number decreases; so the immune system becomes weak and the person is prone to any infection.


69. Where are mucosal associated lymphoid tissues present in the human body and why?

Answer/Explanation

Answer:
Explaination: Mucosal associated lymphoid tissues are present within the lining of the respiratory, digestive and urinogenital tracts; they con-stitute about 50 per cent of the lymphoid tissue.


70. Name the two types of cells in which HIV multiplies, after gaining entry into the human body.

Answer/Explanation

Answer:
Explaination: Macrophages and Helper T-lymphocytes.


71. Retroviruses have no DNA. However, the DNA of the infected host cell does possess viral DNA. How is it possible? [All India 2015; HOTS]

Answer/Explanation

Answer:
Explaination: Retroviruses carry out reverse transcription (formation of DNA on RNA template) as they possess the enzyme, reverse transcrip-tase; the DNA is integrated with host DNA.


72. Why is sharing of injection needles between two individuals not recommended? [Delhi 2013]

Answer/Explanation

Answer:
Explaination: It is to prevent the spread of HIV or hepatitis B through contaminated needles.


73. Why does an AIDS patient suffer from many other infections? [HOTS]

Answer/Explanation

Answer:
Explaination: Due to reduction in the number of helper T-cells, the immune system of the person is weak and he suffers from infections that otherwise could have been overcome.


74. What are protooncogenes?

Answer/Explanation

Answer:
Explaination: Protooncogenes are the genes in normal cells, which when activated under certain conditions, could lead to oncogenic trans-formation of the cells.


75. Indiscriminate diagnostic practices using X-rays, etc. should be avoided. Give one reason. [Delhi 2015]

Answer/Explanation

Answer:
Explaination: X-rays are ionising radiations and can prove to be carcinogenic, i.e. cancer-causing.


76. Mention the useful as well as the harmful drug obtained from the latex of poppy plant. [Foreign 2012]

Answer/Explanation

Answer:
Explaination: Morphine.


77. Write the chemical structure of morphine.

Answer/Explanation

Answer:
Explaination:
Biology MCQs for Class 12 with Answers Chapter 8 Human Health and Disease 1


78. What is heroin chemically?

Answer/Explanation

Answer:
Explaination: Diacetylmorphine.


79. What is meant by drug abuse?

Answer/Explanation

Answer:
Explaination: When drugs are taken for a purpose other than their normal clinical use and in amounts/concentrations or frequency that impair one’s physical, physiological and psychological functions, it constitutes drug abuse.


80. Write the structural formula of a cannabinoid molecule.

Answer/Explanation

Answer:
Explaination:
Biology MCQs for Class 12 with Answers Chapter 8 Human Health and Disease 2


81. (a) Where are cannabinoid receptors present in a human body?
(b) Name the body system affected by cannabinoids.

Answer/Explanation

Answer:
Explaination:
(a) Cannabinoid receptors are present in the brain.
(b) They affect the cardiovascular system.


82. Name two plants other than coca plant that have hallucinogenic properties.

Answer/Explanation

Answer:
Explaination: Atropa belladona and Datura.


83. How does smoking tobacco in human lead to oxygen deficiency in their body? [Delhi 2012]

Answer/Explanation

Answer:
Explaination: Smoking increases the carbon monoxide content of the blood, which reduces the concentration of haem bound oxygen; hence there is oxygen deficiency in their body.


84. Define adolescence.

Answer/Explanation

Answer:
Explaination: Adolescence refers to the period and process of rapid growth and physical and mental development (attitudes and beliefs) from childhood to adulthood.


85. Why do the doses of drugs keep on increasing or lead to greater intake and addiction? [HOTS]

Answer/Explanation

Answer:
Explaination: It is because the tolerance level of the receptors in our body increases; they start responding to higher doses only and hence there is greater intake.


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