Biology is the study of life. Below, You will find a list of Biology MCQ Questions as per the latest prescribed syllabus. Ace up your preparation with the Objective Questions available on Antibiotics and enhance your subject knowledge. Understand the concept clearly by consistently practicing the Multiple Choice Questions and score well in your exams.
MCQ Questions on Antibiotics
1. What is the pH of the fermentation medium for chlortetracycline?
(a) 2-3
(b) 3-4
(c) 5-6
(d) 8-9
Answer
Answer: (c) 5-6.
2. The yield of the antibiotic depends upon __________.
(a) Age of the inoculum
(b) Only the pH of the medium
(c) Composition of the medium
(d) All of the above
Answer
Answer: (d) All of the above.
3. In Penicillium chrysogenum, the maximum antibiotic production occurs during the __________.
(a) The second phase
(b) Third phase
(c) First phase
(d) In all three phases
Answer
Answer: (a) The second phase.
4. The fermentation medium for oxytetracycline consists of__________.
(a) CSL, Ammonium sulfate, sodium chloride and Calcium carbonate
(b) CSL, Ammonium sulfate, ammonium chloride and Calcium carbonate
(c) CSL, starch, Ammonium sulfate, sodium chloride and Calcium carbonate
(d) CSL, starch, Ammonium sulfate, ammonium chloride and Calcium carbonate
Answer
Answer: (d) CSL, starch, Ammonium sulfate, ammonium chloride and Calcium carbonate.
5. At normal the pH value of penicillin remains in__________.
(a) Solvent phase
(b) Precipitates
(c) Aqueous phase
(d) Both (a) and (b)
Answer
Answer: (c) Aqueous phase.
6. In which of the following substances is chlortetracycline soluble?
(a) Water
(b) Ether
(c) Organic solvents
(d) All of the above
Answer
Answer: (a) Water.
7. Which of the following statements are true about penicillin at acidic pH?
(a) Penicillin precipitates
(b) Penicillin remains in the aqueous phase
(c) Penicillin remains in the solvent phase
(d) None of the above
Answer
Answer: (c) At acidic pH penicillin remains in the solvent phase.
8. Which of the following fermentation processes is used in the production of penicillin?
(a) Aerobic fermentation followed by anaerobic fermentation
(b) Anaerobic fermentation
(c) Aerobic fermentation
(d) Anaerobic fermentation followed by aerobic fermentation
Answer
Answer: (c) Aerobic fermentation.
9. Which of the following is the media composition for the production of streptomycin?
(a) Glucose, soybean meal, malt extract, ammonium chloride
(b) Calcium carbonate, soybean meal, glucose, peptone
(c) Ammonium sulphate, soybean meal, peptone, malt extract.
(d) Soybean meal, glucose, peptone, malt extract, sodium chloride
Answer
Answer: (d) Soybean meal, glucose, peptone, malt extract, sodium chloride.
10. Which of the following media composition is used for the production of chlortetracycline?
(a) Calcium Carbonate, Sugar and Ammonium sulfate
(b) Corn steep liquor, Calcium Carbonate, and Ammonium sulfate
(c) Corn steep liquor, Ammonium Chloride. , Calcium Carbonate, and Ammonium sulfate
(d) Sugar, corn steep liquor, Calcium Carbonate, Ammonium sulfate, and Ammonium Chloride.
Answer
Answer: (d) Sugar, corn steep liquor, Calcium Carbonate, Ammonium sulfate, and Ammonium Chloride.
11. After the fermentation process, penicillin is recovered as
(a) Penicillin
(b) Sodium penicillin
(c) Calcium penicillin
(d) Potassium penicillin
Answer
Answer: (d) Potassium penicillin.
12. Which of the following species is used for producing streptomycin?
(a) S. ramosus
(b) S. griseus
(c) S. aerofaciens
(d) S. griseoflavus
Answer
Answer: (b) S. griseus.
13. The high yield of chlortetracycline requires ____________.
(a) No aeration
(b) Controlled aeration
(c) Continuous aeration
(d) Aeration which does not affect the yield
Answer
Answer: (c) Continuous aeration.
14. Which of the following statements are true about the vegetable oil added in the fermentation medium for penicillin?
(a) It acts as a carbon source
(b) It acts as an antifoam agent
(c) It acts as a source of nutrients
(d) All of the above
Answer
Answer: (b) It acts as an antifoam agent.
15. Which of the following events occurs during the second phase of growth of Penicillium chrysogenum?
(a) pH increase
(b) Mycelial mass increases
(c) Both (a) and (b)
(d) Synthesis of penicillin is high
Answer
Answer: (c) Both (a) and (b).
16. Which of the following seeds are used for the inoculum preparation for the fermentation medium for penicillin?
(a) Rice seeds
(b) Corn seeds
(c) Wheat seeds
(d) Barley seeds
Answer
Answer: (d) Barley seeds.
17. Which of the following antibiotics are most likely responsible for hypotension, itching and other side effects?
(a) Aztreonam
(b) Vancomycin
(c) Daptomycin
(d) Linezolid
Answer
Answer: (b) Vancomycin.
18. Which of the following events occurs during the first phase of growth of Penicillium chrysogenum?
(a) A maximum rate occurs by the utilization of lactic acid present in the corn steep liquor
(b) Growth of mycelia
(c) Ammonia is liberated in the medium
(d) All of the above
Answer
Answer: (d) All of the above.
19. What type of side effect is most commonly observed in beta-lactam antibiotics?
(a) Hearing loss
(b) Aplastic anaemia
(c) Allergic reaction
(d) Yellowing of teeth
Answer
Answer: (c) Allergic reaction.
20. Which of the following events occurs during the third phase of growth of Penicillium chrysogenum?
(a) Autolysis of the medium starts
(b) Slight rise in pH due to liberation of ammonia
(c) The concentration of antibiotic increases in the medium
(d) All of the above
Answer
Answer: (d) All of the above.