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MCQ Questions on Molecular Basis Of Inheritance

MCQ Questions on Molecular Basis Of Inheritance

1. The nucleic acid synthesis takes place in
(a) 3’-5’ direction
(b) 5’-3’ direction
(c) Both ways
(d) Any direction

Answer

Answer: (b) 5’-3’ direction


2. What is the nature of the strands of the DNA duplex?
(a) Anti-parallel and complementary
(b) Identical and complementary
(c) Anti=parallel and non-complementary
(d) Dissimilar and non-complementary

Answer

Answer: (a) Anti-parallel and complementary


3. Hershey and Chase’s experiment was based on the principle
(a) Transformation
(b) Translation
(c) Transduction
(d) Transcription

Answer

Answer: (c) Transduction


4. AUG stands for
(a) Alanine
(b) Methionine
(c) N-formyl methionine
(d) Glycine

Answer

Answer: (b) Methionine


5. The reason behind the anti-parallel strand of DNA is
(a) Hydrogen bond
(b) Ionic bond
(c) Phosphodiester bond
(d) Disulphide bond

Answer

Answer: (a) Hydrogen bond


6. In a transcription unit, the promoter is located towards
(a) 5’end of the structural gene
(b) 3’end of the structural gene
(c) 5’end of the template strand
(d) 3’end of the coding strand

Answer

Answer: (a) 5’end of the structural gene


7. The primer in DNA replication is
(a) Small ribonucleotide polymer
(b) Helix destabilizing protein
(c) Small deoxyribonucleotide polymer
(d) Enzyme joining nucleotides of new strands

Answer

Answer: (a) Small ribonucleotide polymer


8. Genetic information is transferred from nucleus to cytoplasm through
(a) RNA
(b) Anticodon
(c) DNA
(d) Lysosomes

Answer

Answer: (a) RNA


9. The enzyme involved in transcription
(a) DNA Polymerase I
(b) DNA Polymerase III
(c) RNA Polymerase
(d) DNA Polymerase II

Answer

Answer: (c) RNA Polymerase


10. Non-sense codons participate in
(a) Releasing t-RNA from polynucleotide chain
(b) Formation of unspecified amino acids
(c) Terminating message of gene-controlled protein synthesis
(d) Conversion of sense DNA into non-sense DNA

Answer

Answer: (c) Terminating message of gene-controlled protein synthesis


11. The proofreading enzyme in DNA replication is
(a) Primase
(b) DNA Polymerase I
(c) Ligase
(d) DNA Polymerase II

Answer

Answer: (b) DNA Polymerase I


12. Select a ribozyme
(a) Peptidyl transferase
(b) Helicase
(c) Ribonuclease-P
(d) Both (a) and (c)

Answer

Answer: (d) Both (a) and (c)


13. Which step does not occur in translation?
(a) Replication
(b) Termination
(c) Elongation
(d) Initiation

Answer

Answer: (a) Replication


14. Select the incorrectly matched pairs
(a) Purines – Nitrogenous bases cytosine, thymine and uracil
(b) Recombinant DNA – DNA formed by joining the DNA segments from two different sources
(c) rRNA – RNA found in ribosomes
(d) ATP – The energy-carrying compound in the cell

Answer

Answer: (a) Purines – Nitrogenous bases cytosine, thymine and uracil


15. The energy source for the elongation process is
(a) Creatine-PO4
(b) GTP
(c) ATP
(d) All of the above

Answer

Answer: (b) GTP


16. The anticodon of initiation codon for protein synthesis is
(a) UUU
(b) AUG
(c) UAC
(d) CAU

Answer

Answer: (c) UAC


17. In lac-operon, which protein is not regulated by the repressor?
(a) Galactosidase
(b) Lactose Permease
(c) Tryptophan
(d) Transacetylase

Answer

Answer: (c) Tryptophan


18. Which enzyme is not produced during lactose catabolism by E.coli?
(a) 𝜷-galactosidase
(b) Lactose Permease
(c) Thiogalactoside transacetylase
(d) Lactose dehydrogenase

Answer

Answer: (d) Lactose dehydrogenase


19. The eukaryotic replication of DNA is
(a) Bidirectional with many origins
(b) Unidirectional with many origins
(c) Bidirectional with a single origin
(d) Unidirectional with a single origin

Answer

Answer: (a) Bidirectional with many origins


20. The amino acid coded by 3 codons is
(a) Proline
(b) Isoleucine
(c) Tryptophan
(d) Serine

Answer

Answer: (b) Isoleucine


21. Spliceosomes are absent in the cells of
(a) Plants
(b) Animals
(c) Bacteria
(d) Fungi

Answer

Answer: (c) Bacteria


22. A molecule that acts as a genetic material must fulfil the following traits, except
(a) It should be structurally and chemically unstable
(b) It should have the ability to generate its replica
(c) It should facilitate slow changes necessary for evolution.
(d) It should be able to express itself in the form of Mendelian characters.

Answer

Answer: (a) It should be structurally and chemically unstable


23. What will the amount of guanine in a DNA if the total amount of adenine and thiamine in the DNA is 45%?
(a) 45%
(b) 65%
(c) 27.5%
(d) 22.3%

Answer

Answer: (c) 27.5%


24. The primary control of gene expression takes place at the level of
(a) Translation
(b) Replication
(c) Transcription
(d) None

Answer

Answer: (c) Transcription


25. The gene sequence that codes for proteins are
(a) Exons
(b) Introns
(c) Intervening sequences
(d) Control regions

Answer

Answer: (a) Exons


26. The process of RNA splicing shows the dominance of
(a) RNA world
(b) DNA world
(c) Microbial world
(d) Protein world

Answer

Answer: (a) RNA world


27. In eukaryotes, RNA II facilitates transcription of
(a) rRNA
(b) mRNA
(c) hnRNA
(d) tRNA

Answer

Answer: (c) hnRNA


28. Human Genome Project led to the development of
(a) Biotechnology
(b) Bioinformatics
(c) Biosystematics
(d) Bioengineering

Answer

Answer: (b) Bioinformatics


29. Which non-radioactive isotope was used by Messelson and Stahl in their experiment?
(a) P32
(b) S35
(c) N15
(d) None

Answer

Answer: (c) N15


30. Histones are
(a) Positively charged and basic amino acids
(b) Positively charged and acidic proteins
(c) Negatively charged and basic proteins
(d) Absent in bacteria

Answer

Answer: (d) Absent in bacteria


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